Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GABA-A receptor / inhibitory neurotransmission: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| GABRA1 | participates_in | gene | 0.40 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Biorhythmic Interference via Controlled Sleep Oscillations | 0.412 | neurodegeneration | Microglia-astrocyte crosstalk amplificat |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 7 hypotheses Top: 0.521
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| A brain-to-gut signal controls intestinal fat absorption. [PMID:39261733] | Lyu Q, Xue W, Liu R, Ma Q, Kasaragod VB, | Nature | 2024 | 1 |
| Epilepsy plus blindness in microdeletion of GABRA1 and GABRG2 in mouse and human [PMID:37703949] | Zhang Q, Forster-Gibson C, Bercovici E, | Exp Neurol | 2023 | 1 |
| Pharmacogenetics of anxiety and depression in Alzheimer's disease. [PMID:36628952] | Cacabelos R, Carril JC, Corzo L, Pego R, | Pharmacogenomics | 2023 | 1 |
| Genetic factors in precocious puberty. [PMID:34665958] | Shim YS, Lee HS, Hwang JS | Clin Exp Pediatr | 2022 | 1 |
| Sleep drives metabolite clearance from the adult brain. [PMID:24136970] | Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Th | Science | 2013 | 1 |
| Prenatal alcohol exposure dysregulates the expression of clock genes and alters [PMID:41086861] | Reina-Campos M, Gallego-Landin I, Medran | Open biology | 2025 | 0 |
| Sleep-improving effect and the potential mechanism of Morus alba L. on mice. [PMID:39255910] | Kong X, Zhou X, Li R, Kang Q, Hao L, Zhu | Fitoterapia | 2024 | 0 |
| Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. [PMID:34381213] | ["Su Z", "Zhang K", "Kappel K", "Li S", | Nature | 2021 | 0 |
| A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa [PMID:32047260] | ["Yan Y", "Shi K", "Teng F", "Chen J", " | Acta pharmacologica Sinica | 2020 | 0 |
| AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In [PMID:32213322] | ["Powell S", "Samulski R", "McCown T"] | Molecular therapy : the journa | 2020 | 0 |
| Precision medicine treatment in acute myeloid leukemia using prospective genomic [PMID:33106665] | ["Burd A", "Levine R", "Ruppert A", "Mim | Nature medicine | 2020 | 0 |
| Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molec [PMID:29937276] | ["Readhead B", "Haure-Mirande J", "Funk | Neuron | 2018 | 0 |
| Formal group insertion into aryl C‒N bonds through an aromaticity destruction-re [PMID:30143605] | ["Han D", "He Q", "Fan R"] | Nature communications | 2018 | 0 |
| Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial ap [PMID:23589839] | ["Nieminen A", "Eskelinen V", "Haikala H | Proceedings of the National Ac | 2013 | 0 |